Chinese Journal of Catalysis ›› 2017, Vol. 38 ›› Issue (3): 469-474.DOI: 10.1016/S1872-2067(17)62586-X

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Synthesis of biaryls using palladium nanoparticles immobilized on peptide nanofibers as catalyst and hydroxybenzotriazole as novel phenylating reagent

Arash Ghorbani-Choghamarani, Zahra Taherinia   

  1. Department of Chemistry, Faculty of Science, Ilam University, P.O. Box 69315516, Ilam, Iran
  • Received:2016-08-28 Revised:2016-10-10 Online:2017-03-18 Published:2017-03-22

Abstract:

Peptide nanofibers decorated with palladium nanoparticles catalyzed direct coupling of aryl halides with hydroxybenzotriazole to afford the corresponding biaryls in good to excellent yields. The coupling reactions proceeded under simple, green, and mild conditions. The peptide nanofibers were used as recyclable supports in the coupling reactions. This approach is the first to use hydroxybenzotriazole as a phenylating agent.

Key words: Peptide nanofiber, Hydroxybenzotriazole, Biaryl, PEG, Palladium