Chinese Journal of Catalysis ›› 2015, Vol. 36 ›› Issue (1): 113-118.DOI: 10.1016/S1872-2067(14)60220-5

• Articles • Previous Articles    

One-pot green synthesis of enamides and 1,3-diynes

Hao Liang, Zhihui Ren, Yaoyu Wang, Zhenghui Guan   

  1. Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University, Xi'an 710127, Shaanxi, China
  • Received:2014-07-19 Revised:2014-09-02 Online:2014-12-31 Published:2014-12-31
  • Supported by:

    This work was supported by the National Natural Science Foundation of China (21272183) and the Fund of the Rising Stars of Shaanxi Province (2012KJXX-26).

Abstract:

A green organic synthetic method combining reductive acylation of ketoximes and oxidative coupling of terminal alkynes was developed. This novel process enables enamides and 1,3-diynes to be synthesized simultaneously in high yields and under mild conditions without the use of terminal reductants/oxidants.

Key words: Green synthesis, Ketoxime, Terminal alkyne, Enamide, 1,3-Diyne