催化学报

催化学报 ›› 2008, Vol. 29 ›› Issue (9): 935-939.

• 研究论文 • 上一篇    下一篇

温和条件下Fe(NO3)3/4-OH-TEMPO催化需氧氧化醇制备羰基化合物

王心亮1,2,梁鑫淼1   

  1. 1 中国科学院大连化学物理研究所, 辽宁大连 116023; 2 中国科学院研究生院, 北京 100049
  • 收稿日期:2008-09-25 出版日期:2008-09-25 发布日期:2012-07-19

Aerobic Oxidation of Alcohols to Carbonyl Compounds Catalyzed by Fe(NO3)3/4-OH-TEMPO under Mild Conditions

WANG Xinliang1,2, LIANG Xinmiao1*   

  1. 1 Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian 116023, Liaoning, China; 2 Graduate University of Chinese Academy of Sciences, Beijing 100049, China
  • Received:2008-09-25 Online:2008-09-25 Published:2012-07-19

PDF

1236

被引次数

83

摘要： 以Fe(NO3)3•9H2O为助剂与廉价的有机小分子催化剂4-羟基-2,2,6,6-四甲基哌啶-N-氧自由基(4-OH-TEMPO)组成催化体系.考察了该催化剂体系上分子氧驱动的氧化含有C=C, N, O和S杂原子的较宽底物范围的伯醇和仲醇氧化生成相应的醛或酮. 结果表明,该反应可在室温条件下在空气中进行,对目的产物的选择性高. 探讨了Fe(NO3)3/4-OH-TEMPO催化氧化醇的反应机理.

关键词: 醇, 选择性氧化, 空气, 4-羟基-2, 2, 6, 6-四甲基哌啶-N-氧自由基, 九水合硝酸铁

Abstract: An efficient, inexpensive, and mild transition-metal oxidation protocol has bee n developed for the Fe(NO3)3/4-OH-TEMPO-catalyzed aerobic selective oxida tion of a wide range of primary and secondary alcohols, which may bear carbon- carbon double bond or O or N or S as heteroatoms, to the corresponding aldehydes and ketones.

Key words: alcohol, selective oxidation, air, 4-hydroxy-2, 2, 6, 6-tetramethyl-piperidyl-1-oxy, ferric nitrate nonahydrate