催化学报 ›› 2015, Vol. 36 ›› Issue (3): 425-431.DOI: 10.1016/S1872-2067(14)60222-9

• 论文 • 上一篇    下一篇

纳米磁性固体酸SO42-/Zr(OH)4-Fe3O4催化水相不对称Aldol反应

邬涛, 万敬伟, 马学兵   

  1. 西南大学化学化工学院, 重庆400715
  • 收稿日期:2014-07-13 修回日期:2014-09-02 出版日期:2015-02-14 发布日期:2015-02-14
  • 通讯作者: 马学兵
  • 基金资助:

    国家自然科学基金(21071116).

Aqueous asymmetric aldol reaction catalyzed by nanomagnetic solid acid SO42-/Zr(OH)4-Fe3O4

Tao Wu, Jingwei Wan, Xuebing Ma   

  1. School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China
  • Received:2014-07-13 Revised:2014-09-02 Online:2015-02-14 Published:2015-02-14
  • Supported by:

    This work was supported by the National Natural Science Foundation of China (21071116).

摘要:

以纳米磁性材料Fe3O4, ZrOCl2·8H2O和硫酸为原料, 在不同焙烧温度下制备了纳米磁性固体酸催化剂SO42-/Zr(OH)4-Fe3O4.详细表征了该磁性固体酸的SO42-负载量、酸分布、表面形貌和孔结构等特性.在含有硝基和氰基强吸电子基苯甲醛的不对称水相Aldol反应中, SO42-/Zr(OH)4-Fe3O4表现出优良的催化性能(83%-100%收率, 86.0%-95.6% ee antianti/syn = 88-96/12-4).该类磁性固体酸可在外加磁体作用下定量地从催化反应体系中分离并回收使用, 重复使用5次未见显著失活.

关键词: 固体酸催化剂, 磁性, Aldol反应, 不对称催化, 水相

Abstract:

Magnetic solid acid catalysts SO42-/Zr(OH)4-Fe3O4 were prepared using magnetic Fe3O4 nanoparticles, ZrOCl2·8H2O, and sulfuric acid as starting materials in the calcination temperature range 110-650 ℃. The properties of the magnetic solid acid, such as loaded SO42- content, acid distribution, surface morphology, and porous structure, were characterized. In the aqueous asymmetric aldol reaction of various benzaldehydes with strong electron-withdrawing groups (R=NO2 and CN), good to excellent catalytic performance (83%-100% yield, 86.0%-95.6% ee anti, and anti/syn=88-96/12-4) was achieved. These nanomagnetic solid acids can be quantitatively recycled from the reaction mixture using an external magnet and reused five times without significant loss of catalytic activity.

Key words: Solid acid catalyst, Magnetism, Aldol reaction, Asymmetric catalysis, Aqueous phase