催化学报

催化学报 ›› 2008, Vol. 29 ›› Issue (9): 901-906.

• 研究论文 • 上一篇    下一篇

三溴异氰脲酸和DABCO-Br作为高效催化剂用于羟基硅烷化

Khodabakhsh NIKNAM, Mohammad Ali ZOLFIGOL, Gholamabbas CHEHARDOLI, Mina DEHGHANI   

  1. 1 伊朗波斯湾大学；2 伊朗布-阿里大学；3 哈马丹医科大学
  • 收稿日期:2008-09-25 出版日期:2008-09-25 发布日期:2012-07-19

Tribromoisocyanuric Acid and DABCO-Br as Efficient Catalysts for the Silylation of Hydroxyl Groups with Hexamethyldisilazane

Khodabakhsh NIKNAM, Mohammad Ali ZOLFIGOL, Gholamabbas CHEHARDOLI, Mina DEHGHANI   

  1. 1 Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran; 2 Faculty of Chemistry, Bu-Ali Sina University, P.O. Box 4135, Hamedan 651783683, Iran; 3 School of Pharmacy, Hamedan University of Medical Sciences, 65178 Hamedan, Iran
  • Received:2008-09-25 Online:2008-09-25 Published:2012-07-19

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摘要： Many primary, secondary, tertiary alcohols, and phenolic hydroxyl groups were effectively converted to their corresponding trimethylsilyl ethers using hexamethyldisilazane in the presence of catalytic amounts of tribromoisocyanuric acid and DABCO-bromine under mild conditions at room temperature with short reaction times in good to excellent yields. Excellent chemoselective silylation of hydroxyl groups in the presence of other functional groups were also observed.

关键词: 三溴异氰脲酸, DABCO-Br, 六甲基二硅氮烷, 硅烷化, 羟基

Abstract: A good range of primary, secondary, tertiary alcohols, and phenolic hydroxyl g ro ups were effectively converted into their corresponding trimethylsilyl ethers wi th hexamethyldisilazane in the presence of catalytic amounts of tribromoisocyanu ric acid and DABCO-bromine under mild conditions at room temperature with short reaction times in good to excellent yields.

Key words: tribromoisocyanuric acid, DABCO-bromine, hexamethyldisilazane, silylation, hydroxyl group